Deciphering the role of active remodeling of cortical actin on the spatiotemporal organization of cell surface molecules using an in vitro assay

As the door of your house, wide open to welcome friends but closed to prevent unexpected visits, the membrane opens to import nutrients into the cell, but stays closed to avoid infections. Dr. Darius Koester is working toward understanding its door code. Koester’s project aims to rebuild and understand the machinery controlling the local membrane structures, and its changes over time. His work may help to develop efficient drug delivery systems or prevention treatments against pathogens that exploit membrane defects.