Longevity, Ageing and Long-term Care
Prevention & Personalised Health
AXA Projects
Switzerland
Impact of cataract surgery and intra-ocular lens replacement on endocrine and molecular ciracdian rythms, sleep and cognitive function in older adults
One of Europe’s foremost sleep scientists, Prof. Christian Cajochen, wants to find out to what extent an aging crystalline lens contributes to disturbances in the body’s circadian rhythm. The question is especially important because circadian rhythm disturbances have such a huge impact on the elderly – from hormonal rhythms, body core temperature and sleep to sleep-wake timing, cognition and mood.
Working with a team of European researchers, his project also focuses on the effects of lens replacement. Special attention is being paid to the effects of blue, relatively short light wavelengths, because replacement lenses often are designed to block blue light. The design is based on the theory that blue light might increase the risk for age-related macular degeneration. This matters because the photosensitive cells in the retina that affect the biological clock are especially sensitive to the blue, shorter wavelength part of the visible light spectrum.
Research results could lead to the development of new therapies to treat the biological clock disruptions that impact the quality of life for innumerable elderly persons. The results could also lead to recommendations for ophthalmologists who prescribe replacement lenses for their elderly patients.
Shedding more ight on aging biological clocks
To add or modify information on this page, please contact us at the following address: community.research@axa.com

Christian
CAJOCHEN
Institution
University of Basel
Country
Switzerland
Nationality
Swiss
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